Right Ventricular Performance in the Fetus With Hypoplastic Left Heart Syndrome

Inter-stage right ventricular remodeling in hypoplastic left heart syndrome

Methods A retrospective analysis of the serial MRI scans of all patients with HLHS who had undergone palliation through to completion of Fontan was undertaken. Re-analysis was undertaken by two members of the research team who had previously shown good intrauser variability. Ethical and institutional approval was obtained. All scans had been performed with general anaesthesia on a Philips 1.5 T...

Right ventricular resynchronization in a child with hypoplastic left heart syndrome.

Evaluation of right ventricular function in fetuses with hypoplastic left heart syndrome using tissue Doppler techniques.

OBJECTIVE The outcome of patients with hypoplastic left heart syndrome (HLHS) is influenced by right ventricular function. This study aimed to investigate whether differences in right ventricular function of fetuses with HLHS are present during gestation. METHODS This was a prospective study comprising 14 fetuses with HLHS (28 measurements obtained in total) and 28 normal control fetuses (31 ...

Hypoplastic left heart syndrome

Hypoplastic left heart syndrome (HLHS) refers to the abnormal development of the left-sided cardiac structures, resulting in obstruction to blood flow from the left ventricular outflow tract. In addition, the syndrome includes underdevelopment of the left ventricle, aorta, and aortic arch, as well as mitral atresia or stenosis. HLHS has been reported to occur in approximately 0.016 to 0.036% of...

Beyond Hypoplastic Left Heart Syndrome: The Spectrum of Congenital Heart Disease Associated with Left Ventricular Hypoplasia

Left ventricular hypoplasia complicates other forms of congenital heart disease in addition to the classic ‘‘hypoplastic left heart syndrome.’’ Within this heterogeneous group, subtle anatomic differences determine surgical management and ultimate prognosis. Thus, an individualized approach is necessary to optimize outcomes in this complex population.